What is Lactobacillus acidophilus strain L-92™?

What is Lactobacillus acidophilus L-92™?

Lactobacillus acidophilus L-92™ is a lactic acid bacteria that has been found to relieve allergy symptoms.

Lactobacillus acidophilus L-92™

The Lactobacillus acidophilus L-92™ was singled out as a lactic acid bacteria with allergy relieving properties, as part of long-running research into lactobacilli. Subsequent research found that the Lactobacillus acidophilus L-92™ relieves allergy symptoms by maintaining a balance between immune cells.

Antigen-specific IgE antibodies in the blood in mice after being given fermented milk with different types of lactobacilli Identification of lactobacilli with allergy relieving properties

How the Lactobacillus acidophilus L-92™ works

The Lactobacillus acidophilus L-92™ has been shown in various tests to be effective in relieving allergies.

Estimated mechanism to relieve allergy symptoms

The Lactobacillus acidophilus L-92™ relieves allergy symptoms by regulating the balance of immune cells.
Under normal circumstances, your body maintains an immune balance, allergy symptoms mean that there is an imbalance in your immune cells and Th2 cells are working too hard.
The Lactobacillus acidophilus L-92™ increases immunoregulatory Treg cells and reduces excessive Th2 cells, thereby helping to restore the imbalance in your immune cells.
This effect means that the Lactobacillus acidophilus L-92™ is able to relieve allergy symptoms by regulating the balance between Th1 and Th2 cells.

(H. Kanzato et al.: Immunobiology.,213,399-408(2008))
(A. Torii et al.: Allergol,Int.,56.293-301(2007))
(Y. Inoue et al.: Arch.Allergy Immunol., 165(4), 247-54(2014))
(M. M. Shar et al.: Biol Pharm Bull., 35(4), 612-6(2012))